COX-1 inhibitor, non-steroidal anti-inflammatory drug. Inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD. Synonyms: 1-(4-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid, Acemetacin EP Impurity B CAS No: 53-86-1 Molecular Formula: C19H16ClNO4 Molecular Weight: 357.79 Appearance: White to off-white solid Purity: 98% Melting Point: 159-161C Solubility: Chloroform (Slightly), Methanol (Slightly) Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
357.79
Reinheit:
98%
Formulierung:
White to off-white solid
CAS Nummer:
[53-86-1]
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