Influenza virus type B is a genus in the virus family Orthomyxoviridae, responsible for acute respiratory illnesses in humans. It varies antigenically from influenza virus types A and C and is not divided into any subtypes. The gradual evolution of Influenza virus type B occurs via a series of mutations known as antigenic drift, in the surface glycoprotein haemagglutinin (HA), enabling the virus to evade the immune system and potentially re-infect the same host. HA glycoproteins from the Influenza virus type B are included in the annually updated trivalent flu vaccine, along with the Influenza virus type A subtypes H3N2 and H1N1. Influenza virus is a single-stranded RNA virus, segmented, 70nm diameter, and enveloped. Strains are described by geographic origin, strain number, year of isolation and hemagglutination (H) and neuraminidase (N) antigens. It is an acute viral disease of the uper respiratory tract characterized by fever, headache, chills, myalgia, weakness, runny nose and sore throat. Cough can be severe. Nausea and vomiting are uncommon. Fatality is generally low, except for those with chronic lung or heart conditions. Applications: Suitable for use in Immunohistochemistry. Not suitable for use in Western Blot. Other applications have not been tested. Recommended Dilution: Immunohistochemistry: frozen sections Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[3L3 2B2]
Isotyp:
IgG2b
Reinheit:
Purified by Protein A affinity chromatography.
Formulierung:
Supplied as a liquid in PBS, pH 7.2. Labeled with horseradish peroxidase (HRP).
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