Interleukin 1 alpha (IL-1a) (MaxLight 490), Rabbit

Artikelnummer: USB-I7663-01K-ML490
Artikelname: Interleukin 1 alpha (IL-1a) (MaxLight 490), Rabbit
Artikelnummer: USB-I7663-01K-ML490
Hersteller Artikelnummer: I7663-01K-ML490
Alternativnummer: USB-I7663-01K-ML490-100
Hersteller: US Biological
Wirt: Rabbit
Kategorie: Antikörper
Immunogen: Recombinant human IL-1 alpha.
MaxLight(TM)490 is a new Blue-Green photostable dye conjugate comparable to DyLight(TM)488, Alexa Fluor(TM)488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm), Emission (515nm), Extinction Coefficient 73,000. IL-1alpha is a non-secreted proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1alpha and IL-1beta binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1beta is a secreted cytokine, IL-1alpha is predominantly a cell-associated cytokine. Applications: FLISA: 0.5ug/ml Western Blot: 0.1-0.2ug/ml Neutralization: 1-2ug/ml Optimal working dilutions to be determined by researcher. Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight(TM)490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
Reinheit: Purified by immunoaffinity chromatography.
Formulierung: Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight(TM)490.