IL1B, ID (Interleukin-1 beta, IL-1 beta, Catabolin, IL1F2) (APC), Rabbit
Artikelnummer:
USB-I7663-20B-APC
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| Artikelname: | IL1B, ID (Interleukin-1 beta, IL-1 beta, Catabolin, IL1F2) (APC), Rabbit |
| Artikelnummer: | USB-I7663-20B-APC |
| Hersteller Artikelnummer: | I7663-20B-APC |
| Alternativnummer: | USB-I7663-20B-APC-200 |
| Hersteller: | US Biological |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | FLISA, IHC, WB |
| Immunogen: | KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 148-174 in the central region of human IL1B. Species Sequence Homology: rabbit and monkey |
| IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. Applications: Suitable for use in FLISA, Western Blot, Flow Cytometry (Not Tested) and Immunohistochemistry. Other applications not tested. Recommended Dilutions: FLISA: 1:1000 Western Blot: 1:100-1:500 Immunohistochemistry: 1:50-1:100 Flow Cytometry (Not Tested): 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody. |
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