Interleukin 4 Induced Protein 1, Recombinant, Human (IL4I1, FIG1, L-amino acid oxidase)
Artikelnummer:
USB-I8426-48
Hersteller Artikelnummer:
I8426-48
Alternativnummer:
USB-I8426-48-20
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Applikation:
ELISA
Interleukin 4 induced protein 1(IL4I1), also known as protein FIG1 and L amino acid oxidase, is encoded by a B cell IL4 inducible gene, FIG1, and is highly expressed in primary metastinal B cell lymphomas (14). It belongs to the flavin monoamine oxidase family, FIG1 subfamily. Enzymological characterization reveals that IL4I1 has L amino acid oxidase activity with preference toward aromatic amino acids. Studies have shown that hI L4I1 inhibited the proliferation of CD3 stimulated T lymphocytes with a similar effect on CD4(+) and CD8(+) T cells (5) . Its inhibitory effect was dependent on enzymatic activity and H2O2 production. Its restricted expression to l ymphoid tissues indicates that it may play an important function in the immune system (1, 4). Chinese Hamster Ovary cell line, CHO-derived Gln22 Ser567, with a C-terminal 6 His tag,. Swiss/UniProt Accession: Q96RQ9 Structure: Monomer Molecular Weight: 61kD, SDS-PAGE: 70-75kD Activity: Measured by its ability to oxidize phenylalanine in a horseradish peroxidase coupled assay. The specific activity is 150pmol/min/ug, as measured under the described conditions. Storage and Stability: Store at -70C. Aliquot to avoid repeated freezing and thawing. Stable for 6 months after receipt at -70C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
