Interleukin 13 (IL-13) (Biotin), IgG1, Clone: [1.B2.1], Rat, Monoclonal

Produktübersicht

• Artikelname: Interleukin 13 (IL-13) (Biotin), IgG1, Clone: [1.B2.1], Rat, Monoclonal
• Artikelnummer: USB-I8435-05-BIOTIN
• Hersteller Artikelnummer: I8435-05-Biotin
• Alternativnummer: USB-I8435-05-BIOTIN-100
• Hersteller: US Biological
• Wirt: Rat
• Kategorie: Antikörper
• Immunogen: Purified recombinant human IL-13

Produktbeschreibung

IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having structural features and functional characteristics with IL-4. However, it only shares about 30% homology with the IL-4 sequence. IL-13 inhibits IL-1 beta, IL-6, IL-8, and TNF-alpha resulting in anti-inammatory effects on monocytes and macrophages. It also induces B cells to proliferate and isotype-switch to the production of IgE. In addition, IL-13 modulates TH2 cell development interfering key roles in the ostracizing of gastrointestinal parasites and in the evolvement of asthma and allergy. Applications: Suitable for use in Neutralizing, ELISA, Western Blot, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Frozen sections Optimal dilutions to be determined by researcher. Hybridoma: Rat spleen cells fused with P3X63-AG8.653 myeloma Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [1.B2.1]
• Isotyp: IgG1
• Reinheit: Purified by Protein A/G affinity chromatography.
• Formulierung: Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with Biotin.