Interleukin 13 (IL-13) (MaxLight 490), IgG1, Clone: [1.B2.1], Rat, Monoclonal

Produktübersicht

• Artikelname: Interleukin 13 (IL-13) (MaxLight 490), IgG1, Clone: [1.B2.1], Rat, Monoclonal
• Artikelnummer: USB-I8435-05-ML490
• Hersteller Artikelnummer: I8435-05-ML490
• Alternativnummer: USB-I8435-05-ML490-100
• Hersteller: US Biological
• Wirt: Rat
• Kategorie: Antikörper
• Immunogen: Purified recombinant human IL-13

Produktbeschreibung

MaxLight(TM) 490 is a new Blue-Green photostable dye conjugate comparable to DyLight(TM)488, Alexa Fluor(TM)488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm), Emission (515nm), Extinction Coefficient 73,000. IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having structural features and functional characteristics with IL-4. However, it only shares about 30% homology with the IL-4 sequence. IL-13 inhibits IL-1 beta, IL-6, IL-8, and TNF-alpha resulting in anti-inammatory effects on monocytes and macrophages. It also induces B cells to proliferate and isotype-switch to the production of IgE. In addition, IL-13 modulates TH2 cell development interfering key roles in the ostracizing of gastrointestinal parasites and in the evolvement of asthma and allergy. Applications: Suitable for use in Neutralizing, FLISA, Western Blot, Flow Cytometry and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Frozen sections Optimal dilutions to be determined by researcher. Hybridoma: Rat spleen cells fused with P3X63-AG8.653 myeloma Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight(TM)490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [1.B2.1]
• Isotyp: IgG1
• Reinheit: Purified by Protein A/G affinity chromatography.
• Formulierung: Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight(TM)490.