Interleukin 13 (IL-13), Clone: [5K214 JES10-5A2], Rat, Monoclonal

Produktübersicht

• Artikelname: Interleukin 13 (IL-13), Clone: [5K214 JES10-5A2], Rat, Monoclonal
• Artikelnummer: USB-I8435-05A
• Hersteller Artikelnummer: I8435-05A
• Alternativnummer: USB-I8435-05A-250,USB-I8435-05A-500
• Hersteller: US Biological
• Wirt: Rat
• Kategorie: Antikörper
• Applikation: ELISA, FC, IF, WB
• Immunogen: Recombinant corresponding to human Interleukin 13 expressed in COS cells.

Produktbeschreibung

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1b, TNF-a, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Applications: Suitable for use in ELISA, Immunofluorescence, Flow Cytometry, Immunohistochemistry, Western Blot and Immunocytochemistry. Use I8435-05AX (Interleukin 13 (IL-13) (Azide Free)) for Neutralization. Other applications not tested. Recommended Dilutions: ELISA: <5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [5K214 JES10-5A2]
• Reinheit: Purified.
• Formulierung: Supplied as a liquid in borate buffered saline, pH 8.2. No preservative added.