Interleukin 15, Recombinant, Human (Interleukin-15, IL-15, IL15)
Artikelnummer:
USB-I8437-10H
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| Artikelname: | Interleukin 15, Recombinant, Human (Interleukin-15, IL-15, IL15) |
| Artikelnummer: | USB-I8437-10H |
| Hersteller Artikelnummer: | I8437-10H |
| Alternativnummer: | USB-I8437-10H-10 |
| Hersteller: | US Biological |
| Kategorie: | Molekularbiologie |
| IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been linked to rheumatoid arthritis, inflammatory bowel disease, and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant Human IL-15 is a 12.9kD protein consisting of 115 amino acid residues. Recombinant protein corresponding to human IL-15, expressed in E. coli. Uniprot/Swiss Accession: P40933 Molecular Weight: ~12.9kD (115aa sequence) Biological Activity: Determined by its ability to stimulate the proliferation of mouse CTLL-2 cells. The expected ED50 is 0.5ng/ml, corresponding to a specific activity of >2x10e6units/mg. Amino Acid Sequence: MNWVNVISDL KKIEDLIQSM HIDATLYTES DVHPSCKVTA MKCFLLELQV ISLESGDASI HDTVENLIIL ANNSLSSNGN VTESGCKECE ELEEKNIKEF LQSFVHIVQM FINTS Applications: Suitable for use in Functional Assays. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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