Livin, Recombinant, Human, aa1-298, His-Tag (Baculoviral IAP Repeat Containing Protein 7, BIRC7, Kidney Inhibitor of Apoptosis Protein, KIAP, Livin Inhibitor of Apotosis, Melanoma Inhibitor of Apoptosis Protein, ML-IAP, RING Finge

Produktübersicht

• Artikelname: Livin, Recombinant, Human, aa1-298, His-Tag (Baculoviral IAP Repeat Containing Protein 7, BIRC7, Kidney Inhibitor of Apoptosis Protein, KIAP, Livin Inhibitor of Apotosis, Melanoma Inhibitor of Apoptosis Protein, ML-IAP, RING Finge
• Artikelnummer: USB-L3180-03
• Hersteller Artikelnummer: L3180-03
• Alternativnummer: USB-L3180-03-100
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

Livin is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING zinc finger (RZF) domain. Livin has direct interaction with several caspases including caspase-3, -7, and -9. This protein inhibits the activation of caspase-9 induced by Apaf-1, cytochrome c, and dATP. Recombinant human Livin fused to His-tag at N-terminus was expressed in E.coli and purified by conventional chromatography techniques. Recombinant corresponding to aa1-298 from human Livin, fused to His-tag at N-terminal, expressed in E. coli. Accession: NP_647478 Molecular Weight: ~34.9kD (318aa) confirmed by MALDI-TOF Amino Acid Sequence: MGPKDSAKCL HRGPQPSHWA AGDGPTQERC GPRSLGSPVL GLDTCRAWDH VDGQILGQLR PLTEEEEEEG AGATLSRGPA FPGMGSEELR LASFYDWPLT AEVPPELLAA AGFFHTGHQD KVRCFFCYGG LQSWKRGDDP WTEHAKWFPS CQFLLRSKGR DFVHSVQETH SQLLGSWDPW EEPEDAAPVA PSVPASGYPE LPTPRREVQS ESAQEPGGVS PAEAQRAWWV LEPPGARDVE AQLRRLQEER TCKVCLDRAV SIVFVPCGHL VCAECAPGLQ LCPICRAPVR SRVRTFLS Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 34.9
• NCBI: 647478
• UniProt: Q96CA5
• Reinheit: 90% by SDS-PAGE
• Formulierung: Supplied as a liquid in 20mM Tris, pH 8.0, 1mM DTT, 0.1M sodium chloride, 2mM EDTA, 20% glycerol.