Macrophage, Monocyte Chemotactic Protein-1, aa24-99, Recombinant, Human (MCP-1, Chemokine C-C Motif Ligand 2, CCL2, GDCF-2, HC11, HSMCR30, JE, MGC9434, Monocyte Chemoattractant Protein 1, Monocyte Chemotactic and Activating Factor
Artikelnummer:
USB-M1203-04H
Hersteller Artikelnummer:
M1203-04H
Alternativnummer:
USB-M1203-04H-100
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Chemokine (C-C motif) ligand 2 (CCL2) is a small cytokine belonging to the CC chemokine family that is also known as monocyte chemotactic protein-1 (MCP-1). CCL2 recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Recombinant human CCL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MQPDAINAPV TCCYNFTNRK ISVQRLASYR RITSSKCPKE AVIFKTIVAK EICADPKQKW VQDSMDHLDK QTQTPKT Molecular Weight: ~10.9kD (97aa) Enzyme Activity: Protein kinase activity not determined. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
