MARK4 (MAP/Microtubule Affinity-regulating Kinase 4, KIAA1860, MAP/Microtubule Affinity-regulating Kinase-like 1, MARKL1, MARKL1L, MARK4L, MARK4S), Goat

Produktübersicht

• Artikelname: MARK4 (MAP/Microtubule Affinity-regulating Kinase 4, KIAA1860, MAP/Microtubule Affinity-regulating Kinase-like 1, MARKL1, MARKL1L, MARK4L, MARK4S), Goat
• Artikelnummer: USB-M2408-01B
• Hersteller Artikelnummer: M2408-01B
• Alternativnummer: USB-M2408-01B-100
• Hersteller: US Biological
• Wirt: Goat
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Immunogen: Synthetic peptide corresponding to IKRKPPPGCSDSPGV, from human MARK4, at C-terminal (NP_113605.2).

Produktbeschreibung

MARK4 contains an N-terminal serine/threonine kinase domain, a central ubiquitin-associated domain, and a C-terminal KA1-associated kinase domain. RT-PCR analysis detects upregulated expression of the gene for MARK4 in nearly all clinical hepatocellular carcinoma cells. Northern blot analysis reveals ubiquitous expression of a 3.6kb transcript, with highest expression in testis. Immunofluorescence microscopy demonstrates homogeneous cytoplasmic expression. Colony-forming assays show that MARK4 antisense reduces the growth of SNU475 cells. It has been suggested that MARK4 provides a growth advantage to cells. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:128,000 Western Blot: 0.3-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Produkteigenschaften

• NCBI: 113605
• UniProt: Q96L34
• Reinheit: Purified by immunoaffinity chromatography.
• Formulierung: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.