MATK, NT (Megakaryocyte-associated Tyrosine Protein Kinase, CHK, CTK, DKFZp434N1212, Hematopoietic Consensus Tyrosine-lacking Kinase, HYL, HHYLTK, HYLTK, Lsk, MGC1708, MGC2101, Protein Kinase HYL, Tyrosine-protein Kinase CTK), Rab
Artikelnummer:
USB-M2418-58D
Hersteller Artikelnummer:
M2418-58D
Alternativnummer:
USB-M2418-58D-200
Hersteller:
US Biological
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, IHC, WB
Immunogen:
Synthetic peptide selected from the N-terminal region of human MATK (KLH).
MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
