MCP2 (Macrophage/Monocyte Chemotactic Protein 2, Monocyte Chemotactic Protein 2, MCP-2, C-C Motif Chemokine 8, Chemokine (C-C Motif) Ligand 8, CCL8, HC14, Monocyte Chemoattractant Protein 2, Small Inducible Cytokine A8, SCYA8, SCY
Artikelnummer:
USB-M2750-08A-ML490
Hersteller Artikelnummer:
M2750-08A-ML490
Alternativnummer:
USB-M2750-08A-ML490-100
Hersteller:
US Biological
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
FLISA, WB
Immunogen:
Recombinant protein corresponding to human MCP-2, expressed in E. coli.
MaxLight(TM)490 is a new Blue-Green photostable dye conjugate comparable to DyLight(TM)488, Alexa Fluor(TM)488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm), Emission (515nm), Extinction Coefficient 73,000. MCP-2 acts as a chemoattractant for monocytes, lymphocytes, eosinophils and basophils, due to its ability to bind to the common MCP receptor, chemokine (C-C motif) receptor 2 (CCR2), and also CCR1 and CCR3. Proteolytic cleavage of MCP-2 into the NH2-terminally truncated form, MCP-2 (6-76), results in the loss of chemotactic activity, forming a functional C-C chemokine inhibitor, which may be important during inflammatory responses. Applications: Suitable for use in FLISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight(TM)490 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
