MCP2, Recombinant, Human (Monocyte Chemotactic Protein-2, CCL8, HC14)
Artikelnummer:
USB-M2750-11
Hersteller Artikelnummer:
M2750-11
Alternativnummer:
USB-M2750-11-2,USB-M2750-11-10
Hersteller:
US Biological
Kategorie:
Molekularbiologie
The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant human MCP-2 is an 8.9kD protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. Amino Acid Sequence: QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP Biological Activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10-100ng/ml. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
