Musashi-1 RNA Binding Protein, Control Peptide (Mi, Msi-1)
Artikelnummer:
USB-M9515-01A
Hersteller Artikelnummer:
M9515-01A
Alternativnummer:
USB-M9515-01A-1
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Applikation:
ELISA, WB
Control peptide for M9515-01 which recognizes Musashi RNA Binding Protein in human and rodent. Musashi1, a neural RNA-binding protein, plays an important role in regulating cell differentiation in precursor cells. Musashi-1 (Msi-1) has been shown to increase the accumulation of tau isoforms in intracellular inclusions in dementia and Parkinsons. The presence of Msi-1 in a significant percentage of neurons containing cytoplasmic inclusions in 2 other neurodegenerative diseases Alzheimers disease and Pick disease suggests that it may play a role in the pathogenesis of these neurodegenerative disorders. Musashi1 has also been detected in human tumor tissues such as gliomas and melanomas, suggesting its involvement in cancer development. Msi-1 also appears to play a vital role in the development of several types of carcinoma such as human hepatoma and may be a useful molecular marker for tumor detection. Applications: Suitable for use in ELISA, Western Blotting. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at 4C for short-term only. Stable for 12 months at -20C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Reinheit:
Purified
Formulierung:
Supplied as a lyophilized powder.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten