| Neomycin Sulfate, 50mg/ml Solution is a convenient, ready to use concentrate which inhibits protein synthesis via ribosomal binding mechanism. Aminoglycoside antibiotic that inhibits translation by binding to the small subunit of prokaryotic ribosomes. Inhibitor of phospholipase C due to binding to inositol phospholipids. Neomycin inhibits phosphatidylcholine-phospholipase D activity. Blocks voltage sensitive Ca2+ channels without affecting Na+/Ca2+ antiporter in nerve cells. Prepared with deionized water in 0.9% saline. 0.2um sterile-filtered with validated membrane filters. CAS No: 1405-10-3 Molecular Formula: C23H46N6O133H2SO4 Molecular Weight: 908.9 Identity: Conforms to USP reference Potency: 600 IU/mg (dry basis) Appearance: Colorless to light amber, clear, complete pH: 5.0-7.5 Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures. |
