Niemann-Pick Disease, Type C1 Gene-Like 1 (NPC1L1, Niemann-Pick C1-like Protein 1, NPC1 like 1, NPC1 Niemann-Pick Disease Type C1 Gene-like 1, NPC1L1 Splice Variant, Truncated Niemann-Pick C1-like Protein 1), Rabbit
Artikelnummer:
USB-N2566-32B
Hersteller Artikelnummer:
N2566-32B
Alternativnummer:
USB-N2566-32B-100
Hersteller:
US Biological
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
ELISA, IF, IHC, WB
Immunogen:
Synthetic peptide mapping to a fragment of residues within aa1000-1100 from rat Niemann-Pick Disease, Type C1 Gene-Like 1.
Dietary consumption and intestinal cholesterol absorption contribute to plasma cholesterol levels, which factor into the risk of coronary heart disease. Niemann-Pick type C1 Like 1 protein (NPC1L1 or NPC3) is enriched in the small intestine and is found in the brush border membrane of enterocytes. It plays a critical role in absorption of intestinal cholesterol. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry, Immunofluorescence/Immunocytochemistry and Electron Microscopy. Other applications not tested. Recommended Dilutions: Western Blot: 2ug/ml detects a band at ~140kD representing NPC1L1 and a non-specific band may be observed at ~45kD depending on the lysate used. Immunofluorescence (IC): 2ug/ml Immunohistochemistry (Paraffin/Frozen): 1:100-1:250 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C. For long-term storage, aliquot and store at 4C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
