PDRG1, aa1-133, Recombinant, Human (p53 and DNA-damage Regulated 1, C20orf126, PDRG)
Artikelnummer:
USB-P3125-70H
Hersteller Artikelnummer:
P3125-70H
Alternativnummer:
USB-P3125-70H-100
Hersteller:
US Biological
Kategorie:
Molekularbiologie
PDRG1, also known as PDRG or C20orf126, is a 133aa protein that localizes to the cytoplasm and belongs to the prefoldin subunit b family. Expressed predominately in normal testicular tissue, PDRG1 is functionally induced by ultraviolet light and is thought to play a role in chaperone-mediated protein folding, possibly playing a role in cellular degradation. It is associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Source: Recombinant corresponding to aa1-133 of human PDRG1 protein, fused to His-tag at N-terminus, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MLSPEAERVL RYLVEVEELA EEVLADKRQI VDLDTKRNQN REGLRALQKD LSLSEDVMVC FGNMFIKMPH PETKEMIEKD QDHLDKEIEK LRKQLKVKVN RLFEAQGKPE LKGFNLNPLN QDELKALKVI LKG Molecular Weight: 17.6kD (153aa) confirmed by MALDI-TOF Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
