Plasminogen Activator Inhibitor Type 1, Wild Type Latent, Rat (HEPES Buffer) (PAI-1)

Produktübersicht

• Artikelname: Plasminogen Activator Inhibitor Type 1, Wild Type Latent, Rat (HEPES Buffer) (PAI-1)
• Artikelnummer: USB-P4256-29X
• Hersteller Artikelnummer: P4256-29X
• Alternativnummer: USB-P4256-29X-500
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

Plasminogen Activator Inhibitor 1 (PAI-1) is a glycoprotein found in plasma that is implicated in the processes of angiogenesis, hemostasis, tumor metastasis, fibrionlysis, ovulation, embryonic development and inflammation. The elevation of PAI-1 has shown to correlate with the prognosis of many cancers including breast cancer. PAI-1 is activated by the glycoprotein vitronectin. Vitronectin binds to PAI-1 and modulates fibrinolysis and cell migration. This binding has proven to be an important inhibitor of the activated form of protein C (APC). Concentration of Active PAI-1: Not detectable by SDS-PAGE Solubility: >2mg/ml and <5mg/ml Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for 6 months after receipt.

Produkteigenschaften

• Molekulargewicht: 43
• Reinheit: 95% (SDS-PAGE)
• Formulierung: Supplied as a liquid in 0.1M HEPES, pH 7.4, 0.1M sodium chloride.