Prostaglandin D2 Synthase (PTGDS) Recombinant, Human, aa23-190, His-Tag

Produktübersicht

• Artikelname: Prostaglandin D2 Synthase (PTGDS) Recombinant, Human, aa23-190, His-Tag
• Artikelnummer: USB-P9053-24M
• Hersteller Artikelnummer: P9053-24M
• Alternativnummer: USB-P9053-24M-50,USB-P9053-24M-100,USB-P9053-24M-250,USB-P9053-24M-500
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

Prostaglandin-H2 D-isomerase, also known as PTGDS, is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. PTGDS is the most abundant protein in the cerebral spinal fluid and recent evidence suggests that PTGDS acts as a beta-amyloid chaperone and may have a role in the deposition of Ab plaques in Alzheimers disease. Recombinant protein corresponding to aa23-190 from human PTGDS, fused to His-tag at N-terminus, expressed in E.coli. Swiss/Uniprot: P41222 Molecular Weight: ~20.9kD (189aa), confirmed by MALDI-TOF Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MAPEAQVSVQ PNFQQDKFLG RWFSAGLASN SSWLREKKAA LSMCKSVVAP ATDGGLNLTS TFLRKNQCET RTMLLQPAGS LGSYSYRSPH WGSTYSVSVV ETDYDQYALL YSQGSKGPGE DFRMATLYSR TQTPRAELKE KFTAFCKAQG FTEDTIVFLP QTDKCMTEQ Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 20.9
• NCBI: 000945
• UniProt: P41222
• Reinheit: 90% (SDS-PAGE)
• Formulierung: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 1mM EDTA, 0.1M sodium chloride, 30% glycerol.