Prostaglandin Transporter, Rat, Control Peptide (PGT)

Produktübersicht

• Artikelname: Prostaglandin Transporter, Rat, Control Peptide (PGT)
• Artikelnummer: USB-P9053-50
• Hersteller Artikelnummer: P9053-50
• Alternativnummer: USB-P9053-50-100
• Hersteller: US Biological
• Kategorie: Molekularbiologie
• Applikation: ELISA, WB

Produktbeschreibung

A 20aa Peptide sequence near the C-terminus of rat PGT Mammalian kidney and liver are critical in maintaining physiological ionic environment. Kidney specializes in removing toxins, drugs, and other organic anions from the blood by a process called renal secretion. Besides kidney, anionic substrates are also transported in other organs, e.g., choroid plexus, eye, airway, and placenta. Several multispecific OATs (OAT1-3, OAT-K1 and OATK2) and OATPs (organic anion transporting polypeptides, oatp1-3, LST-1, and PGT), have been cloned and characterized from various tissues. OATPs family of proteins share significant sequence homology, and general secondary protein structure (up to 12 transmembrane domains with cytoplasmic N and C-terminus). Prostaglandins and thromboxanes play important physiological, pathological, and therapeutical roles in health and disease. PGT (prostaglandin transporter also known as martin F/G), a member of oatp family, mediates transport of PGs (PGD2, PGE1, PGE2, PGF2a) from the circulation. PGT (rat/human 643 aa, 12 TM) is expressed in brain, stomach, ileum, jejunum, and kidney but not in heart or skeletal muscle. Applications: ELISA: 1:10-50K for neat serum and 0.5-1ug/ml for affinity pure.

Produkteigenschaften

• Reinheit: Highly purified
• Formulierung: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide