SNUPN, Recombinant, Human, aa1-360, His-Tag (RNA, U Transporter 1, RNUT1, KPNBL, Snurportin 1, Snurportin-1)

Produktübersicht

• Artikelname: SNUPN, Recombinant, Human, aa1-360, His-Tag (RNA, U Transporter 1, RNUT1, KPNBL, Snurportin 1, Snurportin-1)
• Artikelnummer: USB-R2055-01A
• Hersteller Artikelnummer: R2055-01A
• Alternativnummer: USB-R2055-01A-100,USB-R2055-01A-500
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

SNUPN, also known as KPNBL or RNUT1, is a nuclear import adaptor protein belonging to the Snurportin family. Localizing to the cytoplasm and nucleus, Snurportin-1 contains an N-terminal IBB domain and a trimethylguanosine (m3G)-cap binding domain. It specifically binds the terminal 2,2,7-m3G-cap at the 5 end of U snRNPs and functions to transport U snRNPs into the nucleus via an association with Importin b. Recombinant protein corresponding to aa1-360 from human Snurportin-1, fused to His-Tag at N-terminus, expressed in E. coli. Molecular Weight: ~43.3kD (MALDI-TOF) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MEELSQALAS SFSVSQDLNS TAAPHPRLSQ YKSKYSSLEQ SERRRRLLEL QKSKRLDYVN HARRLAEDDW TGMESEEENK KDDEEMDIDT VKKLPKHYAN QLMLSEWLID VPSDLGQEWI VVVCPVGKRA LIVASRGSTS AYTKSGYCVN RFSSLLPGGN RRNSTAKDYT ILDCIYNEVN QTYYVLDVMC WRGHPFYDCQ TDFRFYWMHS KLPEEEGLGE KTKLNPFKFV GLKNFPCTPE SLCDVLSMDF PFEVDGLLFY HKQTHYSPGS TPLVGWLRPY MVSDVLGVAV PAGPLTTKPD YAGHQLQQIM EHKKSQKEGM KEKLTHKASE NGHYELEHLS TPKLKGSSHS PDHPGCLMEN Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 43.3
• NCBI: 001036053
• UniProt: O95149
• Reinheit: 90% (SDS-PAGE)
• Formulierung: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 0.1M sodium chloride, 10% glycerol.