S100 Protein, beta, Recombinant, Human, aa1-92, His-Tag (S100b)

Artikelnummer: USB-S0052-11M
Artikelname: S100 Protein, beta, Recombinant, Human, aa1-92, His-Tag (S100b)
Artikelnummer: USB-S0052-11M
Hersteller Artikelnummer: S0052-11M
Alternativnummer: USB-S0052-11M-20,USB-S0052-11M-100,USB-S0052-11M-500
Hersteller: US Biological
Kategorie: Molekularbiologie
S100B is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. This protein function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Recombinant protein corresponding to aa1-92 of human S1008B, fused to His-Tag at N-terminal, expressed in E. coli. Accession: NP_006263 Molecular Weight: ~12.8kD (112aa) Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLEEIKE QEVVDKVMET LDNDGDGECD FQEFMAFVAM VTTACHEFFE HE Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molekulargewicht: 12.8
NCBI: 006263
UniProt: P04271
Reinheit: 90% (SDS-PAGE) Chromatographically purified.
Formulierung: Supplied as a liquid in 20mM Tris-HCl, pH 8.0, 1mM DTT, 10% glycerol.