Small ubiquitin-related modifier 2 (SUMO-2) is a member of the SUMO protein family and functions in a manner similar to ubiquitin. However, unlike ubiquitin which targets proteins for degradation, SUMO-2 protein is involved in diverse cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. This protein is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Recombinant human SUMO2 protein was expressed in E. coli and purified by using conventional chromatography. Molecular Weight: 10.6 kD (93aa) (Real molecular weight on SDS-PAGE will be shift up) AA Sequence: MADEKPKEGV KTENNDHINL KVAGQDGSVV QFKIKRHTPL SKLMKAYCER QGLSMRQIRF RFDGQPINET DTPAQLEMED EDTIDVFQQQ TGG Storage and Stability: May be stored at 4C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
