Serpin A9, also known as Centerin, is a member of the Serpin superfamily of serine protease inhibitors (1). Serpins are the most broadly distributed superfamily of protease inhibitors. They are known to inhibit serine proteases and some are known to inhibit caspases and papainlike cysteine proteases. rmSerpin A9 shows inhibition towards trypsin, thrombin, and plasmin and binds DNA and heparin. Its expression is limited to germinal center B cells and lymphoid malignancies with germinal center Bcell maturation. New findings suggest that Serpin A9 could be used as a potential diagnostic marker in the recognition of various germinal center derived lymphomas. NS0 derived, recombinant mouse Serpin A9. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: 12 months from date of receipt, 20 to 70C as supplied. 1 month, 2 to 8C under sterile conditions after reconstitution. 3 months, 20 to 70C under sterile conditions after reconstitution. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
