SNRPF, aa1-86, Recombinant, Human (Small Nuclear Ribonucleoprotein Polypeptide F, snRNP-F, Sm Protein F, SmF, Sm-F, PBSCF)
Artikelnummer:
USB-S1014-96W
Hersteller Artikelnummer:
S1014-96W
Alternativnummer:
USB-S1014-96W-100
Hersteller:
US Biological
Kategorie:
Molekularbiologie
Small nuclear ribonucleoprotein polypeptide F, also known SNRPF, belongs to the snRNP Sm proteins family. There are at least seven isoforms, E, F, G, D1, D2, D3 and B/B. This class of common proteins plays an essential role in the biogenesis of the snRNPs. In addition, these proteins represent the major targets for the so-called anti-Sm auto-antibodies which are diagnostic for systemic lupus erythematosus (SLE). SNRPF aid in the cytoplasmic construction of the UsnRNPs by binding to aconserved Sm site on UsnRNA and forming a stable snRNP core complex. Source: Recombinant corresponding to human SNRPF, fused to His-tag at N-terminus, expressed in E. coli. Molecular Weight: ~11.8kD Sequences of Amino Acids: MGSSHHHHHH SSGLVPRGSH MSLPLNPKPF LNGLTGKPVM VKLKWGMEYK GYLVSVDGYM NMQLANTEEY IDGALSGHLG EVLIRCNNVL YIRGVEEEEE DGEMRE Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
