| A potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Induces differentiation in uman breast cancer cells. Appearance: Supplied as a white to off-white solid Purity: ~90% (HPLC, TLC) Melting Point: 156-158C Solubility: DMSO, Ethanol TLC Conditions: SiO2, Chloroform: Methanol: Water: Acetic Acid, 75: 25: 2: 2, Visualized with UV and by exposure to iodine vapor. Elemental Analysis: Calculated: C: 63.62%, H: 7.63%, N: 10.60% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |