Tau [pS199/pS202] Positive and Negative Control Peptides (Tau Protein, Microtubule-associated Protein, MAP)

Produktübersicht

• Artikelname: Tau [pS199/pS202] Positive and Negative Control Peptides (Tau Protein, Microtubule-associated Protein, MAP)
• Artikelnummer: USB-T1040-09
• Hersteller Artikelnummer: T1040-09
• Alternativnummer: USB-T1040-09-1
• Hersteller: US Biological
• Kategorie: Molekularbiologie

Produktbeschreibung

Tau proteins are important in the assembly of microtubules. In normal brain, tau is localized within the axons of the neurons, but in some neuropathological lesions, it accumulates within the body of the neuron. Tau proteins are thought to be abnormally phosphorylated in certain disease states. Tau has been immunohistochemically localized to neurofibrillary tangles of Alzheimers disease (AD) brains. Tau proteins promote the assembly of tubulin monomers into microtubules and stabilize microtubules. Alternate splicing of tau mRNA, glycosylation, and differential phosphorylation contribute to the heterogeneity of tau. Kit Components: T1040-09A: Positive Control GYSS*PGS*PGTPG (*Phosphorylated) Formula: C45H68N12O24P2 MW: 1223.10D 1x1mg T1040-09B: Negative Control GYSSPGSPGTPG Formula: C45H66N12O18 MW: 1063.10D 1x1mg Applications: Suitable for use as a control in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Reconstitution: Reconstitute each vial with 100ul sterile, ddH2O. The peptides may be gently vortexed or triturated at RT to ensure complete solubilization. If the peptides are found to be slow to dissolve, the pH of the solutions may be neutralized by addition of small volumes (1-2ul) of 1.0N ammonium hydroxide, alternatively, the peptides may be solubilized by addition of small volumes of organic solvent, such as ethanol or DMSO. Storage and Stability: Lyophilized powder may be stored at 4C for short-term only. Stable for 12 months at -20C. Reconstitute (see reconstitution instructions for peptides) and store at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Molekulargewicht: 12231063
• Reinheit: ~90% by HPLC
• Formulierung: Supplied as a lyophilized powder (Trifluoroacetate salt).