Tissue Plasminogen Activator (tPA) (MaxLight 550), Rabbit

Artikelnummer: USB-T5600-10G-ML550
Artikelname: Tissue Plasminogen Activator (tPA) (MaxLight 550), Rabbit
Artikelnummer: USB-T5600-10G-ML550
Hersteller Artikelnummer: T5600-10G-ML550
Alternativnummer: USB-T5600-10G-ML550-100
Hersteller: US Biological
Wirt: Rabbit
Kategorie: Antikörper
Applikation: FLISA, IHC, WB
Immunogen: Recombinant human tPA.
MaxLight(TM)550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor(TM)546, 555, DyLight(TM)549 , Cy3(TM), TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm), Emission (575nm), Extinction Coefficient 150,000. Tissue-type plasminogen activator (tPA) circulating in plasma exists in free forms as well as in tPA-inhibitor complexes. The underlying biochemical mechanism governing coagulation and fibrinolysis involves a controlled cascade of proteolytic reactions characterized by the conversion of serine protease zymogens to enzymes. Depending upon the initiating stimulus, the physiological outcome of these reactions is blood clot formation/dissolution. The relative concentrations of serine protease zymogen, enzyme, or enzyme-inhibitor complex in circulation will vary in accord with the state of vascular damage. Many conventional antigen-based clotting factor-specific immunoassays do not distinguish between zymogen and enzyme. Applications: Suitable for use in FLISA, Immunohistochemistry, and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight(TM)550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
Reinheit: Purified by Protein A affinity chromatography.
Formulierung: Supplied as a liquid in 0.05M sodium phosphate, 0.1M sodium chloride, pH 7.4. No preservative added. Labeled with MaxLight(TM)550.