TRC8 (Translocation in renal carcinoma on Chromosome 8, RNF139, ring finger protein 139, HRCA1, MGC31961, RCA1), Goat

Produktübersicht

• Artikelname: TRC8 (Translocation in renal carcinoma on Chromosome 8, RNF139, ring finger protein 139, HRCA1, MGC31961, RCA1), Goat
• Artikelnummer: USB-T5890
• Hersteller Artikelnummer: T5890
• Alternativnummer: USB-T5890-100
• Hersteller: US Biological
• Wirt: Goat
• Kategorie: Antikörper
• Applikation: ELISA, WB
• Immunogen: Synthetic peptide corresponding to C-HTGAAAEEFNDDT, from the C Terminus of human TRC8 (NP_009149.2).

Produktbeschreibung

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:16000 Western Blot: 0.5-1.5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Produkteigenschaften

• NCBI: 009149
• Reinheit: Purified by antigen immunoaffinity chromatography.
• Formulierung: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.