TLR13 (Toll Like Receptor 13, Toll-like Receptor 13), Rabbit
Artikelnummer:
USB-T8051-30G
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| Artikelname: | TLR13 (Toll Like Receptor 13, Toll-like Receptor 13), Rabbit |
| Artikelnummer: | USB-T8051-30G |
| Hersteller Artikelnummer: | T8051-30G |
| Alternativnummer: | USB-T8051-30G-100 |
| Hersteller: | US Biological |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FC, WB |
| Immunogen: | Synthetic peptide corresponding to aa800-850 of mouse TLR13. |
| TLR13, also known as Toll like receptor 13, is a member of the Toll-like receptor (TLR) family of transmembrane proteins comprised of multiple copies of leucine rich repeats in the extracellular domain and a TIR domain. The exact function of this 991aa containing protein is yet unknown, but reports suggest that it is closely related to TLR3 and participates in the innate immune response to microbial agents. TLR13 binds to and acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and inflammatory response. Applications: Suitable for use in ELISA, Flow Cytometry and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml Flow Cytometry (Intracellular): 1-3ug/10e6 cells Peptide ELISA: 1:100-1:2000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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