TSC 2(S1798) (Tuberin, Tuberous Sclerosis 2 Protein, TSC4), Rabbit
Artikelnummer:
USB-T9100-25J1
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| Artikelname: | TSC 2(S1798) (Tuberin, Tuberous Sclerosis 2 Protein, TSC4), Rabbit |
| Artikelnummer: | USB-T9100-25J1 |
| Hersteller Artikelnummer: | T9100-25J1 |
| Alternativnummer: | USB-T9100-25J1-200 |
| Hersteller: | US Biological |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, IF, IHC, WB |
| Immunogen: | KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1776-1805 of human TSC2. |
| Mutations in TSC2 lead to tuberous sclerosis complex. This protein is believed to be a tumor suppressor and is able to specifically stimulate the intrinsic GTPase activity of the Ras-related protein RAP1A and RAB5. TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. It may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors. Interaction between TSC1 and TSC2 may facilitate vesicular docking. Applications: Suitable for use in ELISA, Western Blot, Immunofluorescence and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Immunofluorescence: 1:10-1:50 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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