Tumor Necrosis Factor alpha (TNF alpha, TNF-alpha, TNF a, TNFa, TNF-a, Cachectin, Differentiation Inducing Factor, DIF, Tumor Necrosis Factor Ligand Superfamily Member 2, TNF Superfamily Member 2, TNFSF2), IgG1, Mouse
Artikelnummer:
USB-T9160-03N
Hersteller Artikelnummer:
T9160-03N
Alternativnummer:
USB-T9160-03N-100
Hersteller:
US Biological
Wirt:
Mouse
Kategorie:
Antikörper
Tumor Necrosis Factor alpha (TNF-alpha) is a 17.3kD multi-functional pro-inflammatory cytokine primarily secreted by macrophages, but also produced by T and B lymphocytes, activated monocytes and fibroblasts. TNF-alpha exists in both a transmembrane and mature soluble form and has many biological properties, including activation of transcription factor NF-KappaB, the induction of apoptosis in various tumor cell lines and the stimulation of cell differentiation and proliferation under certain conditions. Studies have revealed a role for TNF-alpha in inflammation, septic shock, autoimmune disease and rheumatoid arthritis. Applications: Suitable for use in ELISA, Immunohistochemistry, Flow Cytometry, Western Blot, Immunoprecipitation and Neutralization. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50 Western Blot: 1:50 Immunohistochemistry: 1:50 Neutralization: For neutralization of biological acitivity in vitro, dilution must be determined according to the amount of TNF-alpha to be inactivated. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Isotyp:
IgG1
Reinheit:
Purified by Protein G affinity chromatography.
Formulierung:
Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
