UBE2L3, NT (Ubiquitin-conjugating Enzyme E2 L3, Ubiquitin-conjugating Enzyme E2-F1, Ubiquitin-protein Ligase L3, Ubiquitin Carrier Protein L3, L-UBC, UbcH7, UBCE7), Rabbit

Produktübersicht

• Artikelname: UBE2L3, NT (Ubiquitin-conjugating Enzyme E2 L3, Ubiquitin-conjugating Enzyme E2-F1, Ubiquitin-protein Ligase L3, Ubiquitin Carrier Protein L3, L-UBC, UbcH7, UBCE7), Rabbit
• Artikelnummer: USB-U1000-88A
• Hersteller Artikelnummer: U1000-88A
• Alternativnummer: USB-U1000-88A-200
• Hersteller: US Biological
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC, WB
• Immunogen: Synthetic peptide selected from the N-terminal region of human UBE2L3 (KLH).

Produktbeschreibung

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Applications: Suitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-1:500 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Produkteigenschaften

• Reinheit: Purified by ammonium sulfate precipitation
• Formulierung: Supplied as a liquid in PBS, 0.09% sodium azide.