Urocortin 2 (Urocortin-2, UCN2, Urocortin II, Ucn II, UCN-II, Stresscopin-related Peptide, SRP, Urocortin-related Peptide, UR, URP, UCNI), Rabbit

Produktübersicht

• Artikelname: Urocortin 2 (Urocortin-2, UCN2, Urocortin II, Ucn II, UCN-II, Stresscopin-related Peptide, SRP, Urocortin-related Peptide, UR, URP, UCNI), Rabbit
• Artikelnummer: USB-U2575-28A
• Hersteller Artikelnummer: U2575-28A
• Alternativnummer: USB-U2575-28A-200
• Hersteller: US Biological
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA
• Immunogen: Synthetic peptide corresponding to human Urocortin 2.

Produktbeschreibung

Urocortin 2 (Ucn 2), also known as stresscopin-related peptide, is a novel predicted neuropeptide related to corticotropin-releasing factor (CRF). The peptide consisting of 38 amino acid residues was first demonstrated to be expressed centrally and to bind selectively to type 2 CRF receptor (CRFR2). In the rodent, Ucn 2 transcripts were shown to be expressed in the discrete regions of the central nervous system including stress-related cell groups in the hypothalamus and brainstem. More recently, the expression of Ucn 2 transcripts was detected in the olfactory bulb, pituitary, cortex, hypothalamus, and spinal cord. Ucn 2 mRNA was also found to be expressed widely in a variety of peripheral tissues, most highly in the skin and skeletal muscle tissues. Ucn 2-like immunoreactivity was detected by RIA in acid extracts of mouse brain, muscle, and skin. Immunohistochemically Ucn 2 was found in both skin epidermis and adnexal structures and in the skeletal muscle myocytes. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilutions: ELISA: 1:3200 (0.313ug/ml) Optimal dilutions to be determined by the researcher. Amino Acid Sequence: His-Pro-Gly-Ser-Arg-Ile-Val-Leu-Ser-Leu-Asp-Val-Pro-Ile-Gly-Leu-Leu-Gln-Ile-Leu-Leu-Glu-Gln-Ala-Arg- Ala-Arg-Ala-Ala-Arg-Glu-Gln -Ala-Thr-Thr-Asn-Ala-Arg-Ile-Leu-Ala-Arg-Val-NH2 Storage and Stability: Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20C. Reconstituted product is stable for 12 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• Reinheit: Purified by Protein A affinity chromatography
• Formulierung: Supplied as a lyophilized powder from PBS. Reconstitute with 200ul sterile PBS.