A cell-permeable, reversible and selective inhibitor of the deubiquitinating activity of human USP14 (IC50=4-5uM). IU1 promotes cell survival during proteotoxic stress and selectively stimulates ubiquitin-dependent protein degradation in vitro at 34uM. Synonyms: 1-[1-(4-Fluoro-phenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-pyrrolidin-1-yl-ethanone CAS No: 314245-33-5 Molecular Formula: C18H21FN2O Molecular Weight: 300.37 Appearance: White to off-white powder Purity: 98% (HPLC) Solubility: DMF, DMSO, Ethanol: 20mg/ml Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molekulargewicht:
300.37
Reinheit:
98% (HPLC)
Formulierung:
White to off-white powder
CAS Nummer:
[314245-33-5]
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
