VEGF (Vascular Endothelial Growth Factor, Vascular Permeability Factor, VEGFA, VPF) (FITC), IgG1, Clone: [CH-10], Mouse, Monoclonal
Artikelnummer:
USB-V2110-11B-FITC
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| Artikelname: | VEGF (Vascular Endothelial Growth Factor, Vascular Permeability Factor, VEGFA, VPF) (FITC), IgG1, Clone: [CH-10], Mouse, Monoclonal |
| Artikelnummer: | USB-V2110-11B-FITC |
| Hersteller Artikelnummer: | V2110-11B-FITC |
| Alternativnummer: | USB-V2110-11B-FITC-100 |
| Hersteller: | US Biological |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | WB |
| Immunogen: | Recombinant protein corresponding to mouse VEGF. |
| VEGF (Vascular endothelial growth factor, VEGFA, VEGF-A), a dimeric ligand, is among the most potent angiogenic mitogens. VEGF is secreted by tumor cells and other cells exposed to hypoxia. VEGF is a highly specific mitogen for vascular endothelial cells. Seven VEGF isoforms (a, b, c, d, e, f, g) are generated as a result of alternative splicing from a single VEGF gene. All seven isoforms differ in their molecular mass and in biological properties such as their ability to bind to cell-surface heparan-sulfate proteoglycans. The expression of VEGF is potentiated and is secreted by tumor cells in response to hypoxia, by activated oncogenes, and by a variety of cytokines. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Positive Control: Jurkat cell lysate. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody. |
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