XAGE1 (G Antigen Family D Member 2, Cancer/Testis Antigen 12.1, CT12.1, Protein XAGE-1, XAGE1A, GAGED2, XAGE1B, XAGE1C, XAGE1D, XAGE1E), Goat
Artikelnummer:
USB-X0965-01E
Hersteller Artikelnummer:
X0965-01E
Alternativnummer:
USB-X0965-01E-100
Hersteller:
US Biological
Wirt:
Goat
Kategorie:
Antikörper
Applikation:
ELISA
Immunogen:
Synthetic peptide corresponding to CGFGFRRQGEDNT, from GAGED2, at C-terminal (NP_597673.1).
XAGE1 is a member of the XAGE subfamily, which belongs to the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. XAGE1 is strongly expressed in Ewings sarcoma, alveolar rhabdomyosarcoma and normal testis. XAGE1 contains a nuclear localization signal and shares a sequence similarity with other GAGE/PAGE proteins. Because of the expression pattern and the sequence similarity, this protein also belongs to a family of CT (cancer-testis) antigens. Alternative splicing of XAGE1 generates 3 transcript variants, and one of which includes 2 transcripts generated from alternate transcription initiation sites. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.