XIAP (API3, Baculoviral IAP repeat-containing protein 4, BIRC4, hILP, HILP, IAP3, IAP-like protein, ILP1, Inhibitor of apoptosis protein 3, MIHA, Xiap, X-linked IAP, X-linked inhibitor of apoptosis protein), Rabbit

Produktübersicht

• Artikelname: XIAP (API3, Baculoviral IAP repeat-containing protein 4, BIRC4, hILP, HILP, IAP3, IAP-like protein, ILP1, Inhibitor of apoptosis protein 3, MIHA, Xiap, X-linked IAP, X-linked inhibitor of apoptosis protein), Rabbit
• Artikelnummer: USB-X1034
• Hersteller Artikelnummer: X1034
• Alternativnummer: USB-X1034-100
• Hersteller: US Biological
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: WB
• Immunogen: Synthetic peptide corresponding to the N-terminal of human XIAP.

Produktbeschreibung

The human X-chromosome-linked inhibitor of apoptosis protein XIAP is a major member of the inhibitor of apoptosis (IAP) family (1). XIAP functions by direct binding and inhibition of several caspases, including caspase-3, caspase-7 and caspase-9 (2,3). There are three BIR (baculovirus IAP repeat) domains in XIAP: BIR1, BIR2 and BIR3. BIR2 has been shown to be important for the binding and inhibition of caspase-3 and caspase-7 (4,5), and BIR3 is a specific inhibitor of caspase-9 (5). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000, incubate membrane with diluted antibody in 5% nonfat dry milk, 1X TBS, 0.1% Tween-20 at 4C with gentle shaking, overnight. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Produkteigenschaften

• UniProt: P98170
• Reinheit: Purified by Protein A and peptide affinity chromatography.
• Formulierung: Supplied as a liquid in 10mM HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol. No preservative added.