XIAPC (APCI3, Baculoviral IAPC repeat-containing protein 4, BIRC4, hILP, HILP, IAPC3, IAPC-like protein, ILP1, Inhibitor of apoptosis protein 3, MIHA, Xiap, X-linked IAPC, X-linked inhibitor of apoptosis protein) (APC), Rabbit1
Artikelnummer:
USB-X1034-05E-APC
Hersteller Artikelnummer:
X1034-05E-APC
Alternativnummer:
USB-X1034-05E-APC-100
Hersteller:
US Biological
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IHC, WB
Immunogen:
Synthetic peptide corresponding to a thirteen amino acid sequence with the C-terminal region of human XIAP.
XIAP is an endogenous inhibitor of cell death, which functions by suppressing caspases 3, 7, and 9. The protein is also reported to play a a role in the activation of NF kappa B and the regulation of cyclins and cyclin-dependent kinase inhibitors (CDKIs). Regulators of XIAP activity include XAF-1 and Smac. Applications: Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: detects a band of ~57kD in human kidney lysates. Immunohistochemistry (paraffin): Requires antigen retrieval using heat treatment prior to staining of paraffin sections. Optimal dilution determined by the researcher. Recommended Secondary Reagents: Sheep anti rabbit IgG: HRP Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
