Synthetic peptide corresponding to C-LIRETQPISKQH, from the C-Terminus of human XPNPEP1 (NP_065116.2, NP_001161076.1).
Aminopeptidase P1 (APP1), also known as XPNPEP1 (X-prolyl aminopeptidase), is a proline-specific metalloaminopeptidase that specifically catalyzes the removal of any unsubstituted N-terminal amino acid that is adjacent to a penultimate proline residue. Deficiency of X-prolyl aminopeptidase results in excretion of large amounts of imino-oligopeptides in urine. The sequence of human APP1 is 99%, 97%, and 95% identical to that of canine, bovine, and mouse/rat. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32000 Western Blot: 0.3-1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.