ZMPSTE24 (Zinc Metalloproteinase Ste24 Homolog, CAAX Prenyl Protease 1 Homolog, Farnesylated Proteins Converting Enzyme 1, FACE 1, FACE1, FACE-1, FLJ14968, MADB, Prenyl Protein Specific Endoprotease 1, STE24), Rabbit
Artikelnummer:
USB-Z0728-50A
Hersteller Artikelnummer:
Z0728-50A
Alternativnummer:
USB-Z0728-50A-100
Hersteller:
US Biological
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Immunogen:
A synthetic peptide made to a C-terminal portion of the human ZMPSTE24 protein sequence (between residues 400-475). [Swiss-Prot O75844].
ZMPSTE24 is a zinc metalloprotease involved in the post-translational processing of LMNA precursors. Mutations in ZMPSTE24 have been associated with human diseases, often due to the accumulation of LMNA precursors. It is possible that ZMPSTE24, due to its association with LMNA, plays some role in human ageing. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Cellular Localization: Integral membrane, primarily ER Storage and Stability: May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20C. Aliquots are stable for at least 3 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Reinheit:
Purified by peptide immunoaffinity chromatography.
Formulierung:
Supplied as a liquid in Tris-glycine, 150mM sodium chloride, pH 7.2.
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