ZNFN1A3 (Zinc Finger Protein Subfamily 1A3, Aiolos, IKAROS Family Zinc Finger 3, IKZF3) (BSA & Azide Free), IgG2b, Clone: [10B2563], Mouse, Monoclonal
Artikelnummer:
USB-Z0749-10
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| Artikelname: | ZNFN1A3 (Zinc Finger Protein Subfamily 1A3, Aiolos, IKAROS Family Zinc Finger 3, IKZF3) (BSA & Azide Free), IgG2b, Clone: [10B2563], Mouse, Monoclonal |
| Artikelnummer: | USB-Z0749-10 |
| Hersteller Artikelnummer: | Z0749-10 |
| Alternativnummer: | USB-Z0749-10-100 |
| Hersteller: | US Biological |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | ELISA, IF |
| Immunogen: | Recombinant protein corresponding to a portion within aa1-510 of human ZNFN1A3. UniProt Accession: Q9UKT9 |
| This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. Applications: Suitable for use in ELISA and Immunofluorescence. Other applications not tested. Recommended Dilution: Immunofluorescence: HeLa cell. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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