ZNFN1A3 (Zinc Finger Protein Subfamily 1A3, Aiolos, IKAROS Family Zinc Finger 3, IKZF3) (BSA & Azide Free) (PE), IgG2b, Clone: [10B2563], Mouse, Monoclonal
Artikelnummer:
USB-Z0749-10-PE
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| Artikelname: | ZNFN1A3 (Zinc Finger Protein Subfamily 1A3, Aiolos, IKAROS Family Zinc Finger 3, IKZF3) (BSA & Azide Free) (PE), IgG2b, Clone: [10B2563], Mouse, Monoclonal |
| Artikelnummer: | USB-Z0749-10-PE |
| Hersteller Artikelnummer: | Z0749-10-PE |
| Alternativnummer: | USB-Z0749-10-PE-100 |
| Hersteller: | US Biological |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FLISA, IF |
| Immunogen: | Recombinant protein corresponding to a portion within aa1-510 of human ZNFN1A3. UniProt Accession: Q9UKT9 |
| This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. Applications: Suitable for use in FLISA and FLISA and Immunofluorescence Optimal dilutions to be determined by the researcher.. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Hybridoma: Sp2/0 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody. |
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