Rap guanine nucleotide exchange factor (GEF) 4 Adenovirus (Ad-EPAC2)

Produktübersicht

• Artikelname: Rap guanine nucleotide exchange factor (GEF) 4 Adenovirus (Ad-EPAC2)
• Artikelnummer: VBL-1392
• Hersteller Artikelnummer: 1392
• Alternativnummer: VBL-1392
• Hersteller: Vector Biolabs
• Kategorie: Sonstiges
• Alternative Synonym: Rap guanine nucleotide exchange factor (GEF) 4 Adenovirus

Produktbeschreibung

Epac (exchange protein directly activated by cAMP, also designated cAMP-GEFI) and Epac2 (also designated cAMP-GEFII) compose a novel family of cyclic AMP activated guanine-nucleotide exchange factors (GEFs). Both Epac and Epac2 contain cAMP-binding motifs and a motif common to Ras superfamily GEFs. Epac and Epac2 both function to activate Rap1, a Ras-like GTPase that is known to suppress the oncogenic transformation of cells by Ras. Epac is ubiquitously expressed, whereas Epac2 is primarily expressed in the brain and adrenal glands.

Produkteigenschaften

• Konzentration: 1x10 10 PFU/ml
• Puffer: DMEM, 2% BSA, 2.5% Glycerol

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