Platelet-derived growth factor receptor, beta polypeptide Adenovirus (Ad-PDGF-R(beta))

Produktübersicht

• Artikelname: Platelet-derived growth factor receptor, beta polypeptide Adenovirus (Ad-PDGF-R(beta))
• Artikelnummer: VBL-1420
• Hersteller Artikelnummer: 1420
• Alternativnummer: VBL-1420
• Hersteller: Vector Biolabs
• Kategorie: Proteine/Peptide
• Alternative Synonym: Platelet-derived growth factor receptor, beta polypeptide Adenovirus

Produktbeschreibung

The platelet derived growth factor receptor (PDGFR) family comprises PDGFR-(alpha) and PDGFR-(beta), which are structurally related and endowed with protein tyrosine kinase domains. These receptors bind the three PDGF ligand isoforms with different affinities. PDGFR-(alpha) can bind to both A and B subunits of PDGF, while PDGFR-(beta) can only bind the B subunit. Chromosomal translocation of the PDGFR-beta gene is linked with chronic myelomonocytic leukemia (CMML), a myelodysplastic syndrome, and demonstrates the oncogenic potential of the PDGF receptors.

Produkteigenschaften

• Konzentration: 1x10 10 PFU/ml
• Puffer: DMEM, 2% BSA, 2.5% Glycerol

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