Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) Adenovirus (Ad-NFKB1/p105)

Produktübersicht

• Artikelname: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) Adenovirus (Ad-NFKB1/p105)
• Artikelnummer: VBL-1451
• Hersteller Artikelnummer: 1451
• Alternativnummer: VBL-1451
• Hersteller: Vector Biolabs
• Kategorie: Proteine/Peptide
• Alternative Synonym: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) Adenovirus

Produktbeschreibung

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth.

Produkteigenschaften

• Konzentration: 1x10 10 PFU/ml
• Puffer: DMEM, 2% BSA, 2.5% Glycerol

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