Sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) Adenovirus (Ad-SIRT2)

Artikelnummer: VEB-1519
Artikelname: Sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) Adenovirus (Ad-SIRT2)
Artikelnummer: VEB-1519
Hersteller Artikelnummer: 1519
Alternativnummer: VEB-1519
Hersteller: VectorBuilder
Kategorie: Molekularbiologie
Alternative Synonym: Sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae) Adenovirus
The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes, including transcriptional regulation, cell cycle progression, DNA-damage repair and aging. The human sirtuins, which include SIRT1-7, are divided into four main branches: SIRT1-3 are class I, SIRT4 is class II, SIRT5 is class III and SIRT6-7 are class IV. SIRT1 is widely expressed and regulates p53 function through its deacetylation at lysine 382.
Puffer: DMEM, 2% BSA, 2.5% Glycerol