PTEN Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer:
ABB-A0008
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Artikelname: | PTEN Rabbit pAb, Unconjugated, Polyclonal |
Artikelnummer: | ABB-A0008 |
Hersteller Artikelnummer: | A0008 |
Alternativnummer: | ABB-A0008-1000UL,ABB-A0008-50UL,ABB-A0008-200UL,ABB-A0008-500UL,ABB-A0008-100UL,ABB-A0008-20UL,ABB-A0008-5UL |
Hersteller: | ABclonal |
Wirt: | Rabbit |
Kategorie: | Antikörper |
Applikation: | ELISA, IF, IHC-P, WB |
Spezies Reaktivität: | Human, Mouse, Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-186 of human PTEN (NP_000305.3). |
Konjugation: | Unconjugated |
Alternative Synonym: | BZS, DEC, CWS1, GLM2, MHAM, TEP1, MMAC1, PTEN1, 10q23del, PTENbeta, PTEN |
This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a cat |
Klonalität: | Polyclonal |
Molekulargewicht: | 47kDa |
NCBI: | 5728 |
UniProt: | P60484 |
Quelle: | Rabbit |
Reinheit: | Affinity purification |
Sequenz: | MTAIIKEIVSRNKRRYQEDGFDLDLTYIYPNIIAMGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIYNLCAERHYDTAKFNCRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGVMICAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLLKNHL |
Target-Kategorie: | PTEN |
Antibody Type: | Primary Antibody |
Application Verdünnung: | WB,1:100 - 1:500|IHC-P,1:50 - 1:200|IF/ICC,1:50 - 1:200 |
Anwendungsbeschreibung: | Cross-reactivity: Human,Mouse,Rat, Research area: Epigenetics Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Protein phosphorylation,Cancer,Tumor suppressors,Signal Transduction,Kinase,PI3K-Akt Signaling Pathway,mTOR Signaling |